NFL Betting Odds: Weekly Point Spreads & Live Lines
Last updated: May 24, 2026 2:38 pm
If you plan on betting on pro football this season, you are going to want to visit this page often. Here you will find the live NFL odds for every one of this week’s games. That includes all of the current NFL point spreads and totals.
You can also easily view the start time “Time” and rotation number “#” for every matchup.
| Rot | Matchup | Date/Time | Open |  |  |  |  |  |  |  |  |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 101 102 | Panthers Cardinals | Aug/6 8:00 PM | -1 -110 34½ -110 | 35 -110 PK -110 | 35 -110 PK -110 | -1 -110 35 -110 | 35 -110 PK -110 | OFF | OFF | -1½ -105 35½ -112 | 35 -110 PK -110 |
| 451 452 | Patriots Seahawks | Sep/9 8:20 PM | 45 -110 -4 -115 | 45 -110 -4½ -115 | 45 -110 -4½ -114 | 44½ -110 -4½ -110 | 44½ -110 -5½ -110 | 44½ -110 -5½ -110 | 44½ -110 -4½ -115 | 44½ -110 -3½ -115 | 45 -110 -4½ -114 |
| 453 454 | 49ers Rams | Sep/10 8:35 PM | 49 -110 -3 +105 | 49 -110 -3 -110 | 49 -110 -3 -110 | 49 -110 -3 -110 | 49 -110 -3 -110 | 49 -110 -3 -110 | 49½ -110 -2½ -115 | 48½ -110 -2½ -120 | 49 -110 -3 -110 |
| 455 456 | Browns Jaguars | Sep/13 1:00 PM | 39½ -110 -7½ -105 | 39½ -110 -7½ -105 | 39½ -110 -7½ -105 | 40 -110 -7½ -105 | 40 -110 -7½ -110 | 40 -110 -7 -110 | 40½ -105 -7 -115 | 40½ -110 -7 -110 | 39½ -110 -7½ -105 |
| 457 458 | Bucs Bengals | Sep/13 1:00 PM | 52½ -110 -3 +100 | 52½ -110 -3½ -110 | 52½ -110 -3½ -110 | 52 -110 -4 -105 | 52½ -110 -3½ -110 | 52 -110 -3½ -110 | 51½ -110 -3½ -110 | 50½ -115 -3½ -110 | 52½ -110 -3½ -110 |
| 459 460 | Ravens Colts | Sep/13 1:00 PM | -3½ -110 48 -105 | -3½ -110 48 -105 | -3½ -110 48 -105 | -3½ -105 47½ -110 | -3½ -110 48 -110 | -3½ -110 48 -110 | -3½ -115 48½ -110 | -3½ -110 49½ -110 | -3½ -110 48 -105 |
| 461 462 | Falcons Steelers | Sep/13 1:00 PM | 41½ -110 -1½ -120 | 41½ -110 -3 -110 | 41½ -110 -3 -113 | 42 -110 -3 -110 | 41½ -110 -3 -110 | 41½ -110 -3 -110 | 41½ -115 -3 -115 | 42½ -110 -3 -120 | 41½ -110 -3 -113 |
| 463 464 | Bills Texans | Sep/13 1:00 PM | -1½ -105 44½ -105 | -1 -110 44½ -105 | -1 -105 44½ -105 | -1 -105 44 -110 | -1 -110 44½ -110 | -1 -110 44½ -110 | -1½ +100 44½ -115 | -1½ +100 45½ -105 | -1 -105 44½ -105 |
| 465 466 | Bears Panthers | Sep/13 1:00 PM | -3 +100 45½ -110 | -2 -120 45½ -110 | -2½ -115 45½ -110 | -2½ -115 45½ -110 | -2½ -110 46 -110 | -2½ -110 46 -110 | -2½ -115 45½ -110 | -2½ -110 44½ -110 | -2½ -115 45½ -110 |
| 467 468 | Jets Titans | Sep/13 1:00 PM | 38½ -110 -1½ -110 | 38½ -110 -2 -120 | 38½ -110 -2½ -115 | 38½ -110 -2½ -115 | 39 -110 -2½ -110 | 39 -110 -2½ -110 | 38½ -115 -3 -110 | 39½ -110 -3 -115 | 38½ -110 -2½ -115 |
| 469 470 | Saints Lions | Sep/13 1:00 PM | 50 -110 -6½ -110 | 50 -110 -7 -110 | 50 -110 -7 -110 | 49½ -110 -7 -110 | 49½ -110 -7 -110 | 49 -110 -7 -110 | 50½ -105 -7 -110 | 48½ -115 -7 -110 | 50 -110 -7 -110 |
| 471 472 | Cardinals Chargers | Sep/13 4:05 PM | 46 -115 -1½ -105 | 46 -115 -1½ -110 | 46 -115 -1½ -105 | 46 -110 -1½ -110 | 46 -110 -1½ -110 | 46 -110 -1½ -110 | 46½ -110 -1½ -110 | 45½ -110 -11½ -110 | 46 -115 -1½ -105 |
| 473 474 | Dolphins Raiders | Sep/13 4:25 PM | 39½ -110 -3 -115 | 40½ -110 -3½ -105 | 40½ -110 -3 -120 | 40½ -110 -3½ -105 | 40½ -110 -3½ -110 | 40½ -110 -3½ -110 | 40½ -110 -3½ -110 | 41½ -110 -3 -120 | 40½ -110 -3 -120 |
| 475 476 | Commanders Eagles | Sep/13 4:25 PM | 47½ -115 -4 -110 | 47½ -115 -4 -115 | 47½ -115 -4 -115 | 47½ -110 -4 -110 | 47½ -110 -4 -110 | 47½ -110 -4 -110 | 47½ -110 -4½ -110 | 46½ -110 -5½ -110 | 47½ -115 -4 -115 |
| 477 478 | Packers Vikings | Sep/13 4:25 PM | -1½ -110 45½ -110 | 45½ -110 PK -110 | -1 -110 45½ -110 | -1 -110 45½ -110 | 45½ -110 PK -110 | 45 -110 PK -110 | -1½ +100 45½ -110 | -1½ -110 44½ -110 | -1 -110 45½ -110 |
| 479 480 | Cowboys Giants | Sep/13 8:20 PM | -1½ -115 48 -110 | -1½ -115 48 -110 | -2 -105 48 -108 | -2 -110 48 -110 | -2½ -110 48 -110 | -2½ -110 48 -110 | -2½ -110 48½ -110 | -2½ -105 48½ -110 | -2 -105 48 -108 |
| 481 482 | Broncos Chiefs | Sep/14 8:15 PM | 42½ -110 -3 +100 | 42½ -110 -3 -110 | 42½ -110 -2½ -120 | 42½ -110 -3 -105 | 43 -110 -3 -110 | 43 -110 -3 -110 | 42½ -115 -3 -110 | 42½ -110 -2½ -120 | 42½ -110 -2½ -120 |
How to Read the NFL Odds
NFL betting odds are shown in three main formats: moneylines, point spreads, and totals (over/unders).
The moneyline is the simplest. It shows which team is favored and what the payout will be if they win outright. A favorite might be listed at -150, meaning you must risk $150 to win $100, while an underdog at +130 pays $130 on a $100 bet if they pull the upset.
The point spread is designed to level the playing field. The favorite will have to win by more than the listed number (for example, -3.5) to “cover” the spread, while underdog bettors win if their team loses by less than that margin or wins outright.
The total, or over/under, sets the expected combined score of both teams. Bettors simply choose whether the final score will go over or under that number. For example, if the line is 46.5, an outcome of 27–24 would go “over” since the total points equal 51.
Together, these three markets cover the vast majority of NFL wagers, and learning to read them is the first step to becoming a sharper bettor. We go over these in further detail and even more options in our NFL betting guide.
Why Our NFL Odds Page is Valuable
We provide lines from some of the best-known online sportsbooks in the industry as a tool to help you find the best possible line on every game. Different sportsbooks will have slightly different spreads, totals, and moneylines. By scanning our board, you can quickly see where you can get the most favorable number on each of your bets.
It also helps you track market movement. Odds shift during the week as bettors and bookmakers react to injuries, weather, and betting action. Following these changes can tell you where the sharp money is heading or when public sentiment is driving a number away from the opening line. Which is why we also provide the opening NFL point spreads and totals for every game under “Opener.”
It’s our way of showing you the importance of having options. Having multiple books available means you get the best odds when you go to place a wager. It lets you identify value spots and outlier numbers. Each half number matters, especially on the key NFL numbers, because it can turn a loss into a push or a push into a win. By monitoring the odds here, you can put yourself in a position to consistently get the best of the number.
But don’t only look at the point spreads for value. Sometimes the moneyline is mispriced according to a team’s chances of winning, and our NFL spread to money line converter can help find those opportunities.
While this page shows just individual games, we also have the current Vegas Super Bowl odds that are updated each week as well.
How to Beat the NFL Betting Lines
Beating the NFL odds on your own is a difficult task and one that takes a lot of time to master. That’s where our experts come into play. If you want to beat the books consistently, check out our premium picks for a list of all available packages.
You can also purchase plays directly from this page. In the far right column under “Picks,” you will see a link for each game. That will take you to all the current packages that include a play on that specific game.
I’ve put together a list of the top NFL handicappers to follow, but you can see what our handicappers have to offer. Each week, several experts will provide free NFL best bets against the spread or total at no cost.
Looking for advice on how to improve your handicapping skills? We have you covered as well. Our NFL handicapping guide is the ultimate resource for picking more winners.
Struggling to understand something that wasn’t mentioned? Have a question or concern about how to bet on football? I would be happy to help out in any way I can, just shoot me an email at jimmy@boydsbets.com.
More NFL Betting Odds & Lines:
